Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
b-NGF
28.0 59
RA2159 IKK16 2.0
uM
TNF-a 100
ng/mL
2
b-NGF
32.0 49
N2645 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
b-NGF
121.0 64
N2645 IKK16 2.0
uM
TNF-a 100
ng/mL
2
b-NGF
116.0 49
RA2708 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
2
b-NGF
28.0 55
RA2708 IKK16 2.0
uM
TNF-a 100
ng/mL
2
b-NGF
25.0 55
RA2159 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
b-NGF
46.0 41
RA2159 TNF-a 100
ng/mL
2
b-NGF
59.0 56
N2645 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
b-NGF
254.0 43
N2645 TNF-a 100
ng/mL
2
b-NGF
182.0 52
RA2708 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
2
b-NGF
42.0 36
RA2708 TNF-a 100
ng/mL
2
b-NGF
43.0 28
RA2159 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
2
b-NGF
35.0 43
RA2159 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
2
b-NGF
35.0 62
N2645 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
2
b-NGF
153.0 45
N2645 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
2
b-NGF
150.5 46
RA2708 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
2
b-NGF
39.0 47
RA2708 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
2
b-NGF
32.0 35
RA2159 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
2
b-NGF
70.0 47
RA2159 IL-1 alpha 100
ng/mL
2
b-NGF
63.5 34
N2645 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
2
b-NGF
256.0 47
N2645 IL-1 alpha 100
ng/mL
2
b-NGF
290.0 50
RA2708 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
2
b-NGF
67.0 36
RA2708 IL-1 alpha 100
ng/mL
2
b-NGF
54.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
2
b-NGF
31.0 42