Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 37.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MIF
 24.5 56
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 22.0 66
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MIF
 75.5 52
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 47.5 58
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 20.0 43
RA2159 TNF-a 100
ng/mL
 2
MIF
 21.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 23.0 46
N2645 TNF-a 100
ng/mL
 2
MIF
 19.0 46
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 23.0 49
RA2708 TNF-a 100
ng/mL
 2
MIF
 23.0 34
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 32.0 49
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 37.0 52
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 36.0 70
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 35.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 27.0 42
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 28.0 40
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 32.0 53
RA2159 IL-1 alpha 100
ng/mL
 2
MIF
 28.0 49
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 33.0 54
N2645 IL-1 alpha 100
ng/mL
 2
MIF
 32.0 42
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 31.0 49
RA2708 IL-1 alpha 100
ng/mL
 2
MIF
 218.5 42
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIF
 25.0 55
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIF
 24.5 52