Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 90.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 81.0 51
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 98.0 78
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 94.5 50
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 96.5 62
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 108.0 61
RA1869 TNF-a 100
ng/mL
 3
IL-1RA
 140.5 60
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 104.0 51
N2759 TNF-a 100
ng/mL
 3
IL-1RA
 112.0 59
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 125.0 55
RA1931 TNF-a 100
ng/mL
 3
IL-1RA
 130.0 49
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 124.5 52
N2586 TNF-a 100
ng/mL
 3
IL-1RA
 123.5 50
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-1RA
 20.5 42
RA1869 IKK16 2.0
uM
 3
IL-1RA
 18.0 51
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-1RA
 20.0 47
N2759 IKK16 2.0
uM
 3
IL-1RA
 20.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-1RA
 22.0 57
RA1931 IKK16 2.0
uM
 3
IL-1RA
 21.0 65
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-1RA
 23.5 60
N2586 IKK16 2.0
uM
 3
IL-1RA
 23.0 51
RA1869 Tofacitinib 0.3
uM
 3
IL-1RA
 21.0 61
RA1869 3
IL-1RA
 23.0 48
N2759 Tofacitinib 0.3
uM
 3
IL-1RA
 22.0 54
N2759 3
IL-1RA
 20.0 73