Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 86.0 | 57 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 75.0 | 50 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 76.0 | 62 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 82.0 | 55 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 78.0 | 51 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 69.0 | 45 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 75.0 | 45 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 77.0 | 62 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 84.0 | 51 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 84.0 | 44 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 87.0 | 39 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 84.0 | 55 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | TNFb | 79.0 | 39 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 28.5 | 50 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 31.0 | 47 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 34.5 | 62 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 38.0 | 45 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 30.0 | 54 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 38.0 | 45 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 31.0 | 56 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 30.0 | 47 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 32.0 | 55 | |
RA1869 | TNF-a | 100 | ng/mL | 3 | TNFb | 36.0 | 63 | ||||
N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | TNFb | 35.0 | 70 | |
N2759 | TNF-a | 100 | ng/mL | 3 | TNFb | 31.0 | 41 |