Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
TNFb
86.0 57
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
TNFb
75.0 50
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
TNFb
76.0 62
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
TNFb
82.0 55
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
TNFb
78.0 51
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
TNFb
69.0 45
RA1869 IL-1 alpha 100
ng/mL
3
TNFb
75.0 45
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
TNFb
77.0 62
N2759 IL-1 alpha 100
ng/mL
3
TNFb
84.0 51
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
TNFb
84.0 44
RA1931 IL-1 alpha 100
ng/mL
3
TNFb
87.0 39
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
TNFb
84.0 55
N2586 IL-1 alpha 100
ng/mL
3
TNFb
79.0 39
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
TNFb
28.5 50
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
3
TNFb
31.0 47
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
TNFb
34.5 62
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
3
TNFb
38.0 45
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
TNFb
30.0 54
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
3
TNFb
38.0 45
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
TNFb
31.0 56
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
3
TNFb
30.0 47
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
TNFb
32.0 55
RA1869 TNF-a 100
ng/mL
3
TNFb
36.0 63
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
TNFb
35.0 70
N2759 TNF-a 100
ng/mL
3
TNFb
31.0 41