Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 2
TNFb
 39.0 32
N2645 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 35.0 39
N2645 IKK16 2.0
uM
 2
TNFb
 40.0 43
RA2708 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 42.5 44
RA2708 IKK16 2.0
uM
 2
TNFb
 38.0 52
RA2159 Tofacitinib 0.3
uM
 2
TNFb
 39.0 52
RA2159 2
TNFb
 36.5 56
N2645 Tofacitinib 0.3
uM
 2
TNFb
 33.0 38
N2645 2
TNFb
 36.0 59
RA2708 Tofacitinib 0.3
uM
 2
TNFb
 40.0 39
RA2708 2
TNFb
 42.0 36
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
TNFb
 39.0 66
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
TNFb
 38.0 35
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
TNFb
 41.0 54
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
TNFb
 41.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
TNFb
 43.0 46
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
TNFb
 42.0 52
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
TNFb
 33.0 34
RA2159 TNF-a 100
ng/mL
 2
TNFb
 32.0 40
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
TNFb
 45.5 34
N2645 TNF-a 100
ng/mL
 2
TNFb
 37.0 44
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
TNFb
 34.5 32
RA2708 TNF-a 100
ng/mL
 2
TNFb
 48.0 32
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 102.0 55
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 96.0 51