Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 36.0 43
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 58.0 44
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 32.0 41
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 40.5 36
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 37.0 40
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 48.0 35
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 35.0 41
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 53.0 39
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 64.0 47
RA1869 TNF-a 100
ng/mL
 3
LIF
 72.0 56
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 49.5 38
N2759 TNF-a 100
ng/mL
 3
LIF
 52.5 32
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 54.0 48
RA1931 TNF-a 100
ng/mL
 3
LIF
 54.0 32
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 57.0 39
N2586 TNF-a 100
ng/mL
 3
LIF
 57.0 60
RA1869 5z-7-oxozeaenol 0.6
uM
 3
LIF
 38.0 37
RA1869 IKK16 2.0
uM
 3
LIF
 42.0 42
N2759 5z-7-oxozeaenol 0.6
uM
 3
LIF
 37.0 45
N2759 IKK16 2.0
uM
 3
LIF
 39.0 39
RA1931 5z-7-oxozeaenol 0.6
uM
 3
LIF
 33.0 63
RA1931 IKK16 2.0
uM
 3
LIF
 38.0 33
N2586 5z-7-oxozeaenol 0.6
uM
 3
LIF
 35.0 39
N2586 IKK16 2.0
uM
 3
LIF
 34.0 29
RA1869 Tofacitinib 0.3
uM
 3
LIF
 36.0 45