Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 80.0 69
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 115.0 55
RA2159 TNF-a 100
ng/mL
 2
IL-1RA
 117.0 44
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 82.0 50
N2645 TNF-a 100
ng/mL
 2
IL-1RA
 99.0 55
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 105.0 53
RA2708 TNF-a 100
ng/mL
 2
IL-1RA
 90.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 23.0 47
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 29.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 27.0 68
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 26.0 74
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 25.0 63
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 34.0 73
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 76.0 71
RA2159 IL-1 alpha 100
ng/mL
 2
IL-1RA
 75.0 55
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 41.5 44
N2645 IL-1 alpha 100
ng/mL
 2
IL-1RA
 40.0 47
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 71.0 39
RA2708 IL-1 alpha 100
ng/mL
 2
IL-1RA
 73.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 24.0 63
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 27.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 25.5 70
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 23.0 49
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 26.0 69
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 28.5 60