Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SDF1-a
 12.0 35
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SDF1-a
 13.0 51
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SDF1-a
 11.0 35
RA2159 TNF-a 100
ng/mL
 2
SDF1-a
 14.0 42
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SDF1-a
 12.0 40
N2645 TNF-a 100
ng/mL
 2
SDF1-a
 12.0 50
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SDF1-a
 15.0 25
RA2708 TNF-a 100
ng/mL
 2
SDF1-a
 12.5 28
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 19.0 33
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 18.0 38
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 12.5 48
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 15.5 38
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 13.0 35
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 20.0 34
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 18.0 38
RA2159 IL-1 alpha 100
ng/mL
 2
SDF1-a
 13.0 37
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 13.0 39
N2645 IL-1 alpha 100
ng/mL
 2
SDF1-a
 16.0 36
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SDF1-a
 16.0 39
RA2708 IL-1 alpha 100
ng/mL
 2
SDF1-a
 16.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SDF1-a
 16.0 45
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
SDF1-a
 11.0 42
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SDF1-a
 12.0 33
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
SDF1-a
 11.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SDF1-a
 10.0 44