Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 11.0 37
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 18.0 40
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 11.0 43
RA1869 TNF-a 100
ng/mL
 1
SDF1-a
 9.0 37
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 17.0 59
N2759 TNF-a 100
ng/mL
 1
SDF1-a
 15.5 56
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 14.0 53
RA1931 TNF-a 100
ng/mL
 1
SDF1-a
 14.0 45
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
SDF1-a
 14.0 34
N2586 TNF-a 100
ng/mL
 1
SDF1-a
 15.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 17.5 40
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 15.0 35
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 21.0 52
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 18.0 35
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 17.0 47
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 20.0 58
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 17.0 43
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 16.0 54
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 16.0 37
RA1869 IL-1 alpha 100
ng/mL
 1
SDF1-a
 14.5 34
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 21.0 44
N2759 IL-1 alpha 100
ng/mL
 1
SDF1-a
 18.5 44
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 17.0 41
RA1931 IL-1 alpha 100
ng/mL
 1
SDF1-a
 15.0 53
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
SDF1-a
 19.5 24