Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2708 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 29.0 | 55 | |
RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 29.5 | 86 | |
RA2159 | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 28.0 | 77 | ||||
N2645 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 24.0 | 67 | |
N2645 | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 27.0 | 84 | ||||
RA2708 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 27.0 | 54 | |
RA2708 | Poly(I:C) | 2 | ug/mL | 4 | IFN-a2 | 30.0 | 38 | ||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 46.0 | 73 | |
RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 41.0 | 71 | |
N2645 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 40.5 | 86 | |
N2645 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 41.0 | 72 | |
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 40.0 | 73 | |
RA2708 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 39.0 | 53 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 44.5 | 64 | |
RA2159 | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 47.5 | 64 | ||||
N2645 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 44.0 | 59 | |
N2645 | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 42.5 | 62 | ||||
RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 42.0 | 61 | |
RA2708 | IL-1 alpha | 100 | ng/mL | 4 | IFN-a2 | 42.0 | 35 | ||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 25.0 | 69 | |
RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 29.5 | 56 | |
N2645 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 23.5 | 60 | |
N2645 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 24.0 | 75 | |
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 28.0 | 88 | |
RA2708 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 4 | IFN-a2 | 28.5 | 76 |