Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIG
 129.0 60
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 56.5 50
RA2159 TNF-a 100
ng/mL
 2
MIG
 43.5 54
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 39.5 60
N2645 TNF-a 100
ng/mL
 2
MIG
 48.0 48
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 125.5 40
RA2708 TNF-a 100
ng/mL
 2
MIG
 115.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 27.5 48
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 28.0 71
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 27.0 56
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 31.5 62
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 34.5 46
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 47.0 44
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 34.0 58
RA2159 IL-1 alpha 100
ng/mL
 2
MIG
 40.0 45
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 47.0 48
N2645 IL-1 alpha 100
ng/mL
 2
MIG
 47.0 49
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 58.0 35
RA2708 IL-1 alpha 100
ng/mL
 2
MIG
 64.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 19.5 68
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 20.0 56
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 14.0 66
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 14.0 45
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 24.0 58
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 29.0 41