Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 TNF-a 100
ng/mL
 2
IL-12 (p70)
 77.0 40
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 35.0 50
N2645 TNF-a 100
ng/mL
 2
IL-12 (p70)
 40.0 53
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 49.5 48
RA2708 TNF-a 100
ng/mL
 2
IL-12 (p70)
 53.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 40.0 63
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 45.5 56
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 32.0 58
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 40.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 41.0 65
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 55.0 52
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 65.0 50
RA2159 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 73.0 57
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 54.0 49
N2645 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 50.0 33
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 62.0 55
RA2708 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 56.0 29
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 39.5 44
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 47.5 60
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 37.5 56
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 36.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 42.0 67
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 46.0 57
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 51.0 68
RA2159 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 71.0 58