Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 1
IL-7
 20.0 49
N2586 Tofacitinib 0.3
uM
 1
IL-7
 16.0 63
N2586 1
IL-7
 13.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-7
 14.0 43
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-7
 19.0 62
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-7
 18.0 61
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-7
 23.0 67
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-7
 26.0 60
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-7
 26.0 42
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-7
 18.5 56
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-7
 19.5 56
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-7
 27.0 35
RA1869 TNF-a 100
ng/mL
 1
IL-7
 23.5 48
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-7
 19.0 81
N2759 TNF-a 100
ng/mL
 1
IL-7
 27.0 50
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-7
 31.0 66
RA1931 TNF-a 100
ng/mL
 1
IL-7
 25.5 56
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-7
 20.5 60
N2586 TNF-a 100
ng/mL
 1
IL-7
 19.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 16.0 75
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 15.5 38
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 18.0 58
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 16.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 21.0 70
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 19.0 33