Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 19.5 64
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 19.0 80
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 17.0 72
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 18.0 68
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 23.0 72
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 20.0 84
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 21.0 75
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 34.0 83
RA1869 Poly(I:C) 2
ug/mL
 3
G-CSF
 54.0 61
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 41.0 63
N2759 Poly(I:C) 2
ug/mL
 3
G-CSF
 43.0 84
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 46.0 67
RA1931 Poly(I:C) 2
ug/mL
 3
G-CSF
 79.5 58
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
G-CSF
 83.0 56
N2586 Poly(I:C) 2
ug/mL
 3
G-CSF
 88.5 54
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 19.0 61
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 25.5 66
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 14.0 66
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 35.0 70
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 15.0 62
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 39.0 50
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 15.0 83
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 25.0 77
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
G-CSF
 145.0 65
RA1869 IL-1 alpha 100
ng/mL
 3
G-CSF
 159.0 58