Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | 1 | MIP-1A | 27.0 | 40 | |||||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 52.0 | 33 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 60.0 | 51 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 60.0 | 59 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 65.0 | 49 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 63.0 | 40 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 68.0 | 51 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 58.0 | 92 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 63.0 | 51 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 87.0 | 41 | |
RA1869 | TNF-a | 100 | ng/mL | 1 | MIP-1A | 84.0 | 48 | ||||
N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 93.0 | 46 | |
N2759 | TNF-a | 100 | ng/mL | 1 | MIP-1A | 123.0 | 47 | ||||
RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 86.0 | 59 | |
RA1931 | TNF-a | 100 | ng/mL | 1 | MIP-1A | 94.0 | 51 | ||||
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MIP-1A | 77.0 | 58 | |
N2586 | TNF-a | 100 | ng/mL | 1 | MIP-1A | 71.0 | 56 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 22.0 | 54 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 23.0 | 49 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 21.0 | 48 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 23.0 | 59 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 24.0 | 53 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 26.5 | 48 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 26.0 | 55 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MIP-1A | 23.5 | 52 |