Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IL-1 alpha 100
ng/mL
 2
MCP-1 (MCAF)
 2921.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 55.0 67
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 182.5 50
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 107.0 50
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 99.5 40
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 76.0 49
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 246.5 40
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 2052.0 39
RA2159 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 4323.0 57
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 1497.0 52
N2645 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 2456.0 56
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 3823.0 40
RA2708 Poly(I:C) 2
ug/mL
 2
MCP-1 (MCAF)
 2988.0 26
RA2159 5z-7-oxozeaenol 0.6
uM
 2
MCP-1 (MCAF)
 30.0 64
RA2159 IKK16 2.0
uM
 2
MCP-1 (MCAF)
 35.5 40
N2645 5z-7-oxozeaenol 0.6
uM
 2
MCP-1 (MCAF)
 47.0 38
N2645 IKK16 2.0
uM
 2
MCP-1 (MCAF)
 34.0 42
RA2708 5z-7-oxozeaenol 0.6
uM
 2
MCP-1 (MCAF)
 65.5 36
RA2708 IKK16 2.0
uM
 2
MCP-1 (MCAF)
 63.0 45
RA2159 Tofacitinib 0.3
uM
 2
MCP-1 (MCAF)
 41.5 48
RA2159 2
MCP-1 (MCAF)
 54.5 46
N2645 Tofacitinib 0.3
uM
 2
MCP-1 (MCAF)
 58.0 26
N2645 2
MCP-1 (MCAF)
 79.0 40
RA2708 Tofacitinib 0.3
uM
 2
MCP-1 (MCAF)
 87.0 32
RA2708 2
MCP-1 (MCAF)
 72.0 39