Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 1994.5 | 54 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 3927.5 | 46 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 434.0 | 59 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 273.0 | 63 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 2022.0 | 38 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 1633.5 | 44 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 895.0 | 63 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 957.0 | 60 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8949.5 | 48 | |
| RA1869 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8228.0 | 45 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6639.0 | 61 | |
| N2759 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8100.0 | 54 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8303.0 | 51 | |
| RA1931 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8532.0 | 45 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7951.0 | 58 | |
| N2586 | TNF-a | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7010.5 | 58 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 105.0 | 63 | |
| RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 862.0 | 43 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 108.0 | 43 | |
| N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 359.0 | 49 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 139.0 | 61 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 934.0 | 46 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 191.5 | 50 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 384.0 | 44 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7897.0 | 45 |