Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 85.5 30
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 89.5 34
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 46.5 36
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 66.0 32
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 89.0 27
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 72.5 38
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 94.5 30
RA2159 TNF-a 100
ng/mL
 4
IL-4
 126.0 17
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 101.5 24
N2645 TNF-a 100
ng/mL
 4
IL-4
 99.0 29
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 62.5 22
RA2708 TNF-a 100
ng/mL
 4
IL-4
 98.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 21.5 24
RA2159 IKK16 2.0
uM
 4
IL-4
 23.5 34
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 22.0 20
N2645 IKK16 2.0
uM
 4
IL-4
 22.0 43
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 22.5 30
RA2708 IKK16 2.0
uM
 4
IL-4
 26.0 30
RA2159 Tofacitinib 0.3
uM
 4
IL-4
 19.5 24
RA2159 4
IL-4
 22.0 27
N2645 Tofacitinib 0.3
uM
 4
IL-4
 19.0 36
N2645 4
IL-4
 24.5 24
RA2708 Tofacitinib 0.3
uM
 4
IL-4
 30.0 21
RA2708 4
IL-4
 22.0 29
RA2159 4
IL-4
 19.0 15