Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 17.0 31
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 14.5 36
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 12.0 45
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 17.0 40
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 15.0 37
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 19.0 33
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 20.0 36
RA2159 IL-1 alpha 100
ng/mL
 4
IL-13
 29.0 29
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 13.0 29
N2645 IL-1 alpha 100
ng/mL
 4
IL-13
 23.0 36
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 24.0 18
RA2708 IL-1 alpha 100
ng/mL
 4
IL-13
 23.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 17.0 29
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 20.0 45
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 10.0 26
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 15.0 38
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 18.5 40
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 14.5 38
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 20.5 32
RA2159 TNF-a 100
ng/mL
 4
IL-13
 30.0 20
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 21.0 33
N2645 TNF-a 100
ng/mL
 4
IL-13
 16.0 25
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 18.0 39
RA2708 TNF-a 100
ng/mL
 4
IL-13
 16.0 25
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-13
 16.5 32