Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 59.0 55
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 63.0 49
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 45.0 57
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 53.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 51.0 51
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 50.0 49
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 62.5 56
RA2159 TNF-a 100
ng/mL
 2
PDGF-BB
 69.0 60
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 73.0 54
N2645 TNF-a 100
ng/mL
 2
PDGF-BB
 63.0 56
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
PDGF-BB
 59.0 48
RA2708 TNF-a 100
ng/mL
 2
PDGF-BB
 54.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 25.0 47
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 28.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 31.0 70
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 31.5 66
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 24.0 45
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 32.0 79
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 54.0 63
RA2159 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 50.0 59
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 37.0 58
N2645 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 40.5 60
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 52.0 53
RA2708 IL-1 alpha 100
ng/mL
 2
PDGF-BB
 48.5 48
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
PDGF-BB
 25.0 75