Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 58.5 68
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 51.0 76
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 55.0 67
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 46.0 49
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 55.0 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 71.0 59
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 79.0 59
RA1869 TNF-a 100
ng/mL
 1
PDGF-BB
 84.0 53
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 46.5 86
N2759 TNF-a 100
ng/mL
 1
PDGF-BB
 64.5 50
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 87.5 64
RA1931 TNF-a 100
ng/mL
 1
PDGF-BB
 83.0 55
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
PDGF-BB
 72.5 64
N2586 TNF-a 100
ng/mL
 1
PDGF-BB
 75.0 67
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 25.0 60
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 24.0 58
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 24.0 51
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 26.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 23.5 60
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 27.0 43
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 24.0 41
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 24.0 67
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 50.0 53
RA1869 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 54.0 47
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
PDGF-BB
 48.0 31