Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 686.5 60
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 755.0 54
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 917.0 77
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1098.5 80
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 793.0 61
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1191.5 64
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1602.0 54
RA1869 IL-1 alpha 100
ng/mL
 3
VEGF
 2381.0 64
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1547.0 73
N2759 IL-1 alpha 100
ng/mL
 3
VEGF
 1296.0 72
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1673.0 61
RA1931 IL-1 alpha 100
ng/mL
 3
VEGF
 2520.5 50
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
VEGF
 1164.5 72
N2586 IL-1 alpha 100
ng/mL
 3
VEGF
 1315.0 62
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
VEGF
 1028.5 48
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
VEGF
 1394.0 67
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
VEGF
 713.0 57
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
VEGF
 979.5 58
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
VEGF
 1241.0 73
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
VEGF
 1194.0 57
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
VEGF
 859.0 56
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
VEGF
 1202.0 75
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
VEGF
 1474.0 71
RA1869 TNF-a 100
ng/mL
 3
VEGF
 1921.0 67
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
VEGF
 760.0 59