Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-1B
 16.5 36
N2645 IKK16 2.0
uM
 4
IL-1B
 15.0 60
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-1B
 16.0 52
RA2708 IKK16 2.0
uM
 4
IL-1B
 15.0 40
RA2159 Tofacitinib 0.3
uM
 4
IL-1B
 17.5 50
RA2159 4
IL-1B
 20.5 32
N2645 Tofacitinib 0.3
uM
 4
IL-1B
 18.5 42
N2645 4
IL-1B
 15.5 34
RA2708 Tofacitinib 0.3
uM
 4
IL-1B
 20.0 26
RA2708 4
IL-1B
 19.0 28
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 21.5 42
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 36.0 43
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 15.5 38
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 17.5 30
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 17.0 56
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 91.0 47
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 50.5 38
RA2159 Poly(I:C) 2
ug/mL
 4
IL-1B
 70.0 27
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 21.0 25
N2645 Poly(I:C) 2
ug/mL
 4
IL-1B
 35.5 34
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 84.5 38
RA2708 Poly(I:C) 2
ug/mL
 4
IL-1B
 78.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 16.0 45
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 26.0 47
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 29.0 43