Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-2
 50.0 66
N2645 IKK16 2.0
uM
 2
IL-2
 62.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-2
 59.0 52
RA2708 IKK16 2.0
uM
 2
IL-2
 63.0 75
RA2159 Tofacitinib 0.3
uM
 2
IL-2
 55.0 55
RA2159 2
IL-2
 62.0 47
N2645 Tofacitinib 0.3
uM
 2
IL-2
 61.5 64
N2645 2
IL-2
 59.0 57
RA2708 Tofacitinib 0.3
uM
 2
IL-2
 58.0 61
RA2708 2
IL-2
 55.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 87.0 47
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 86.0 46
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 82.5 60
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 84.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 87.5 58
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 81.0 45
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 100.0 57
RA2159 TNF-a 100
ng/mL
 2
IL-2
 110.0 39
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 76.5 38
N2645 TNF-a 100
ng/mL
 2
IL-2
 89.0 39
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 86.5 40
RA2708 TNF-a 100
ng/mL
 2
IL-2
 100.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 51.0 55
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 61.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 60.0 51