Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
RANTES
 159.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
RANTES
 78.0 59
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
RANTES
 2341.0 45
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
RANTES
 23685.0 59
RA2159 TNF-a 100
ng/mL
 2
RANTES
 25124.0 65
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
RANTES
 2802.0 56
N2645 TNF-a 100
ng/mL
 2
RANTES
 7506.0 49
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
RANTES
 14377.0 51
RA2708 TNF-a 100
ng/mL
 2
RANTES
 15100.0 40
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 70.0 58
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 191.0 70
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 43.0 58
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 111.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 37.0 55
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 196.0 52
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 10993.0 53
RA2159 IL-1 alpha 100
ng/mL
 2
RANTES
 9238.0 45
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 2400.5 54
N2645 IL-1 alpha 100
ng/mL
 2
RANTES
 2653.0 34
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
RANTES
 3013.0 51
RA2708 IL-1 alpha 100
ng/mL
 2
RANTES
 2736.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
RANTES
 1483.0 62
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
RANTES
 4590.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
RANTES
 115.0 75
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
RANTES
 60.0 65