Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 23.5 60
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 32.0 65
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 70.0 63
RA2159 IL-1 alpha 100
ng/mL
 2
TNF-a
 78.0 53
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 37.0 44
N2645 IL-1 alpha 100
ng/mL
 2
TNF-a
 37.0 55
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 81.0 52
RA2708 IL-1 alpha 100
ng/mL
 2
TNF-a
 73.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 24.5 80
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 26.0 54
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 22.5 74
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 21.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 22.5 56
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 26.0 67
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 42.5 78
RA2159 Poly(I:C) 2
ug/mL
 2
TNF-a
 56.0 63
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 25.0 66
N2645 Poly(I:C) 2
ug/mL
 2
TNF-a
 26.5 60
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 55.5 56
RA2708 Poly(I:C) 2
ug/mL
 2
TNF-a
 62.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 25.0 58
RA2159 IKK16 2.0
uM
 2
TNF-a
 22.0 63
N2645 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 24.0 55
N2645 IKK16 2.0
uM
 2
TNF-a
 23.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 27.0 60