Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 487.5 60
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 496.0 45
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 553.0 75
RA2159 TNF-a 100
ng/mL
 2
GM-CSF
 580.0 63
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 491.0 60
N2645 TNF-a 100
ng/mL
 2
GM-CSF
 526.0 53
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 500.0 52
RA2708 TNF-a 100
ng/mL
 2
GM-CSF
 477.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 412.0 57
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 412.0 73
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 413.0 83
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 425.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 410.0 74
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 440.0 76
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 526.0 72
RA2159 IL-1 alpha 100
ng/mL
 2
GM-CSF
 513.0 54
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 451.5 68
N2645 IL-1 alpha 100
ng/mL
 2
GM-CSF
 483.0 51
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 513.0 52
RA2708 IL-1 alpha 100
ng/mL
 2
GM-CSF
 526.5 60
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 397.0 74
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 421.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 419.0 67
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 402.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 446.0 67