Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 322.0 73
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 348.0 67
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 452.5 56
RA1869 TNF-a 100
ng/mL
 1
GM-CSF
 429.0 75
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 336.0 75
N2759 TNF-a 100
ng/mL
 1
GM-CSF
 395.5 50
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 438.0 66
RA1931 TNF-a 100
ng/mL
 1
GM-CSF
 446.5 82
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 379.0 67
N2586 TNF-a 100
ng/mL
 1
GM-CSF
 381.0 72
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 234.5 68
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 243.5 58
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 229.5 66
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 237.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 217.5 74
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 247.5 68
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 215.0 52
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 222.0 59
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 386.5 72
RA1869 IL-1 alpha 100
ng/mL
 1
GM-CSF
 381.0 57
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 344.0 66
N2759 IL-1 alpha 100
ng/mL
 1
GM-CSF
 373.5 58
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 353.0 58
RA1931 IL-1 alpha 100
ng/mL
 1
GM-CSF
 358.0 55
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 403.0 45