Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Poly(I:C) 2
ug/mL
 4
MMP-3
 258.0 45
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 37.0 41
N2645 Poly(I:C) 2
ug/mL
 4
MMP-3
 84.5 54
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 2601.5 34
RA2708 Poly(I:C) 2
ug/mL
 4
MMP-3
 3013.5 36
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 79.5 52
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 128.5 56
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 43.0 64
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 204.0 60
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 297.5 50
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 6898.0 59
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 5006.0 49
RA2159 IL-1 alpha 100
ng/mL
 4
MMP-3
 3155.0 49
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 1670.0 53
N2645 IL-1 alpha 100
ng/mL
 4
MMP-3
 1540.5 52
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MMP-3
 25730.0 47
RA2708 IL-1 alpha 100
ng/mL
 4
MMP-3
 39153.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MMP-3
 77.0 49
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MMP-3
 109.0 77
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MMP-3
 45.0 61
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MMP-3
 56.5 50
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MMP-3
 383.0 39
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MMP-3
 2167.0 66
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
MMP-3
 169.0 55
RA2159 TNF-a 100
ng/mL
 4
MMP-3
 263.0 44