Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 4
MMP-2
186.0 38
N2645 Tofacitinib 0.3
uM
4
MMP-2
87.0 37
N2645 4
MMP-2
62.5 50
RA2708 Tofacitinib 0.3
uM
4
MMP-2
412.0 34
RA2708 4
MMP-2
409.5 46
RA2159 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
MMP-2
195.0 39
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
MMP-2
286.0 41
N2645 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
MMP-2
47.0 47
N2645 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
MMP-2
75.0 50
RA2708 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
MMP-2
298.0 56
RA2708 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
MMP-2
443.0 35
RA2159 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
MMP-2
258.5 36
RA2159 Poly(I:C) 2
ug/mL
4
MMP-2
260.5 34
N2645 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
MMP-2
68.0 39
N2645 Poly(I:C) 2
ug/mL
4
MMP-2
64.0 23
RA2708 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
MMP-2
428.0 18
RA2708 Poly(I:C) 2
ug/mL
4
MMP-2
345.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
4
MMP-2
130.0 33
RA2159 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
4
MMP-2
251.0 47
N2645 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
4
MMP-2
59.0 42
N2645 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
4
MMP-2
65.5 38
RA2708 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
4
MMP-2
367.0 53
RA2708 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
4
MMP-2
397.0 40
RA2159 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
4
MMP-2
250.5 60
RA2159 IL-1 alpha 100
ng/mL
4
MMP-2
314.0 40