Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | 4 | MMP-2 | 186.0 | 38 | |||||||
N2645 | Tofacitinib | 0.3 | uM | 4 | MMP-2 | 87.0 | 37 | ||||
N2645 | 4 | MMP-2 | 62.5 | 50 | |||||||
RA2708 | Tofacitinib | 0.3 | uM | 4 | MMP-2 | 412.0 | 34 | ||||
RA2708 | 4 | MMP-2 | 409.5 | 46 | |||||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 195.0 | 39 | |
RA2159 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 286.0 | 41 | |
N2645 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 47.0 | 47 | |
N2645 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 75.0 | 50 | |
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 298.0 | 56 | |
RA2708 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 443.0 | 35 | |
RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 258.5 | 36 | |
RA2159 | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 260.5 | 34 | ||||
N2645 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 68.0 | 39 | |
N2645 | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 64.0 | 23 | ||||
RA2708 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 428.0 | 18 | |
RA2708 | Poly(I:C) | 2 | ug/mL | 4 | MMP-2 | 345.0 | 33 | ||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 130.0 | 33 | |
RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 251.0 | 47 | |
N2645 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 59.0 | 42 | |
N2645 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 65.5 | 38 | |
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 367.0 | 53 | |
RA2708 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 397.0 | 40 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 250.5 | 60 | |
RA2159 | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 314.0 | 40 |