Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IL-1 alpha 100
ng/mL
 3
MMP-1
 26357.0 51
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 22135.0 39
N2759 IL-1 alpha 100
ng/mL
 3
MMP-1
 28206.0 37
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 16181.0 31
RA1931 IL-1 alpha 100
ng/mL
 3
MMP-1
 10184.0 47
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 26540.0 80
N2586 IL-1 alpha 100
ng/mL
 3
MMP-1
 29106.5 58
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 3985.5 40
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 13112.0 51
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 390.0 37
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 3291.0 38
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 6635.0 65
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 6890.0 43
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 700.5 38
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 7599.0 48
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 19865.0 42
RA1869 TNF-a 100
ng/mL
 3
MMP-1
 19066.5 48
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 26368.5 50
N2759 TNF-a 100
ng/mL
 3
MMP-1
 24908.0 54
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 8168.0 59
RA1931 TNF-a 100
ng/mL
 3
MMP-1
 8589.5 44
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 24212.0 69
N2586 TNF-a 100
ng/mL
 3
MMP-1
 28206.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 3
MMP-1
 4009.0 45
RA1869 IKK16 2.0
uM
 3
MMP-1
 4976.0 37