Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA1931 | 1 | MMP-1 | 6534.0 | 41 | |||||||
N2586 | Tofacitinib | 0.3 | uM | 1 | MMP-1 | 1482.0 | 31 | ||||
N2586 | 1 | MMP-1 | 1679.0 | 37 | |||||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 3066.0 | 39 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 11180.0 | 37 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 987.0 | 27 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 1639.5 | 20 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 8432.5 | 16 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 6597.0 | 39 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 918.0 | 37 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 3451.0 | 22 | |
RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 16951.5 | 32 | |
RA1869 | TNF-a | 100 | ng/mL | 1 | MMP-1 | 23391.0 | 25 | ||||
N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 28457.0 | 33 | |
N2759 | TNF-a | 100 | ng/mL | 1 | MMP-1 | 28513.5 | 68 | ||||
RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 7988.0 | 22 | |
RA1931 | TNF-a | 100 | ng/mL | 1 | MMP-1 | 9730.0 | 60 | ||||
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | MMP-1 | 19100.0 | 23 | |
N2586 | TNF-a | 100 | ng/mL | 1 | MMP-1 | 18507.0 | 15 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 3056.0 | 19 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 8430.5 | 40 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 619.0 | 27 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 3421.0 | 37 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 5185.0 | 57 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | MMP-1 | 6858.0 | 19 |