Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 1
MMP-1
6534.0 41
N2586 Tofacitinib 0.3
uM
1
MMP-1
1482.0 31
N2586 1
MMP-1
1679.0 37
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MMP-1
3066.0 39
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MMP-1
11180.0 37
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MMP-1
987.0 27
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MMP-1
1639.5 20
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MMP-1
8432.5 16
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MMP-1
6597.0 39
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
1
MMP-1
918.0 37
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
1
MMP-1
3451.0 22
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MMP-1
16951.5 32
RA1869 TNF-a 100
ng/mL
1
MMP-1
23391.0 25
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MMP-1
28457.0 33
N2759 TNF-a 100
ng/mL
1
MMP-1
28513.5 68
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MMP-1
7988.0 22
RA1931 TNF-a 100
ng/mL
1
MMP-1
9730.0 60
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
1
MMP-1
19100.0 23
N2586 TNF-a 100
ng/mL
1
MMP-1
18507.0 15
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
3056.0 19
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
8430.5 40
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
619.0 27
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
3421.0 37
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
5185.0 57
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
6858.0 19