Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 56.0 | 71 | |
| RA2159 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 54.0 | 68 | |
| RA2159 | JNK-IN-11 | 0.3 | uM | 1 | IL12(p40) | 60.5 | 52 | ||||
| N2586 | EGF | 100 | ng/mL | 1 | IL12(p40) | 51.0 | 50 | ||||
| N2586 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 65.0 | 62 | |
| N2586 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 60.0 | 57 | |
| N2586 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 51.0 | 61 | |
| N2586 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 55.5 | 58 | |
| N2586 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 1 | IL12(p40) | 55.0 | 51 | |
| N2586 | JNK-IN-11 | 0.3 | uM | 1 | IL12(p40) | 57.0 | 36 | ||||
| RA2159 | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 71.0 | 60 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 67.0 | 64 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 67.5 | 56 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 65.0 | 53 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 62.5 | 52 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 79.0 | 55 | |
| RA2159 | 1 | IL12(p40) | 48.5 | 62 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 62.0 | 41 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 65.0 | 50 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 66.0 | 49 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 69.5 | 58 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 69.0 | 39 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL12(p40) | 86.0 | 47 | |
| N2586 | 1 | IL12(p40) | 60.0 | 52 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL12(p40) | 109.0 | 59 |