Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | IGF-I | 100 | ug/mL | 1 | IL-16 | 21.0 | 58 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-16 | 21.5 | 78 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-16 | 19.0 | 51 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-16 | 17.0 | 57 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-16 | 17.0 | 34 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-16 | 21.0 | 43 | |
| N2586 | 1 | IL-16 | 15.0 | 47 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-16 | 29.0 | 61 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 31.0 | 61 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 34.0 | 73 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 29.5 | 56 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 37.0 | 51 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 33.5 | 52 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | IL-16 | 35.0 | 68 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 28.0 | 67 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 28.0 | 57 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 25.0 | 43 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 32.5 | 52 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-16 | 26.0 | 52 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | IL-16 | 17.0 | 73 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-16 | 18.5 | 48 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-16 | 16.5 | 44 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-16 | 17.0 | 58 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-16 | 14.0 | 30 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | IL-16 | 21.0 | 36 |