Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PD184352 0.1
uM
 Leptin 1
ng/mL
 3
MCP3
 60.5 70
N2586 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 3
MCP3
 55.5 76
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 3
MCP3
 71.0 59
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 3
MCP3
 48.5 74
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
MCP3
 57.0 55
RA2159 Adiponectin 5
ng/mL
 3
MCP3
 44.5 74
RA2159 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
MCP3
 36.5 72
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 36.5 66
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 36.0 56
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 37.0 73
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
MCP3
 37.0 50
N2586 Adiponectin 5
ng/mL
 3
MCP3
 94.0 69
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
MCP3
 84.0 80
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 75.5 64
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 82.0 54
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
MCP3
 68.5 40
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
MCP3
 67.0 66
RA2159 IGF-I 100
ug/mL
 3
MCP3
 24.0 74
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
MCP3
 28.0 67
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
MCP3
 24.0 64
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
MCP3
 20.0 67
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
MCP3
 24.0 67
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
MCP3
 26.0 63
RA2159 3
MCP3
 28.0 71
N2586 IGF-I 100
ug/mL
 3
MCP3
 78.0 61