Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
MCP3
 29.5 62
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
MCP3
 26.5 64
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MCP3
 22.0 54
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MCP3
 24.0 54
RA2159 Ruxolitinib 0.3
uM
 2
MCP3
 27.5 52
N2586 IL-6 100
ug/mL
 2
MCP3
 54.0 73
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
MCP3
 59.0 77
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
MCP3
 56.0 71
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
MCP3
 65.5 54
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
MCP3
 36.0 60
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
MCP3
 48.0 51
N2586 Ruxolitinib 0.3
uM
 2
MCP3
 53.0 63
RA2159 IL-17A 100
ng/mL
 2
MCP3
 30.0 64
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 32.5 50
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MCP3
 31.0 67
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 29.5 66
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 28.0 55
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MCP3
 26.5 32
RA2159 Tofacitinib 0.3
uM
 2
MCP3
 21.0 37
N2586 IL-17A 100
ng/mL
 2
MCP3
 69.5 40
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 80.0 71
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
MCP3
 59.0 15
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 100.0 20
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
MCP3
 53.0 37
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
MCP3
 64.5 52