Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 1
IL-1RA
 51.0 54
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 54.0 59
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 52.0 63
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 53.0 61
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 48.0 48
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 39.0 47
N2586 EO1428 1.0
uM
 1
IL-1RA
 25.5 30
RA2159 IL-1 alpha 100
ng/mL
 1
IL-1RA
 41.0 71
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 37.5 50
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 27.0 57
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 46.0 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 46.0 65
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 25.0 73
RA2159 PI103 0.1
uM
 1
IL-1RA
 26.0 63
N2586 IL-1 alpha 100
ng/mL
 1
IL-1RA
 53.0 65
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 43.0 63
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 44.0 64
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 53.5 54
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 53.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 35.0 39
N2586 PI103 0.1
uM
 1
IL-1RA
 24.0 49
RA2159 IL-6 100
ug/mL
 1
IL-1RA
 33.0 55
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
IL-1RA
 25.0 78
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
IL-1RA
 23.0 85
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
IL-1RA
 32.5 68