Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 78.5 | 44 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 71.0 | 50 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 92.5 | 58 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 85.0 | 50 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 73.0 | 61 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 80.0 | 65 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 79.0 | 36 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 84.0 | 52 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 80.0 | 37 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | SDF1-a | 71.0 | 75 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | SDF1-a | 25.5 | 58 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 17.0 | 48 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 15.0 | 56 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 28.0 | 45 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 15.5 | 42 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 20.0 | 33 | |
| N2586 | Leptin | 1 | ng/mL | 1 | SDF1-a | 42.0 | 30 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 41.0 | 57 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 36.0 | 53 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 48.0 | 32 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 37.0 | 38 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | SDF1-a | 40.0 | 48 | |
| RA2159 | 1 | SDF1-a | 0 | ||||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | SDF1-a | 0 | |||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | SDF1-a | 0 |