Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
TNF-a 100
ng/mL
 0
IFN-a2
 15.0 40
IL-1 alpha 100
ng/mL
 0
IFN-a2
 18.0 81
IL-6 100
ug/mL
 0
IFN-a2
 19.0 69
IL-17A 100
ng/mL
 0
IFN-a2
 14.5 62
EGF 100
ng/mL
 0
IFN-a2
 16.0 61
IGF-I 100
ug/mL
 0
IFN-a2
 14.5 44
Adiponectin 5
ng/mL
 0
IFN-a2
 390.0 51
Leptin 1
ng/mL
 0
IFN-a2
 17.0 58
Visfatin 1
ng/mL
 0
IFN-a2
 17.0 51
Poly(I:C) 2
ug/mL
 0
IFN-a2
 16.0 36
0
SDF1-a
 17.0 69
RA2159 1
SDF1-a
 28.0 72
RA2159 PD184352 0.1
uM
 1
SDF1-a
 31.0 86
RA2159 Lestaurtinib 0.3
uM
 1
SDF1-a
 22.0 89
RA2159 Ruxolitinib 0.3
uM
 1
SDF1-a
 24.0 66
RA2159 Tofacitinib 0.3
uM
 1
SDF1-a
 28.0 62
RA2159 IKK16 2.0
uM
 1
SDF1-a
 27.0 64
RA2159 1
SDF1-a
 35.0 87
N2586 1
SDF1-a
 52.0 53
N2586 PD184352 0.1
uM
 1
SDF1-a
 49.5 66
N2586 Lestaurtinib 0.3
uM
 1
SDF1-a
 31.0 67
N2586 Ruxolitinib 0.3
uM
 1
SDF1-a
 50.0 50
N2586 Tofacitinib 0.3
uM
 1
SDF1-a
 51.5 46
N2586 IKK16 2.0
uM
 1
SDF1-a
 36.5 42
N2586 1
SDF1-a
 64.5 20