Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 21.0 | 65 | |
| RA2159 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 20.5 | 50 | |
| RA2159 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 24.0 | 57 | |
| N2586 | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 49.0 | 59 | ||||
| N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 50.5 | 62 | |
| N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 39.0 | 63 | |
| N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 57.0 | 71 | |
| N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 50.0 | 60 | |
| N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IFN-a2 | 42.0 | 59 | |
| RA2159 | Leptin | 1 | ng/mL | 3 | IFN-a2 | 19.5 | 54 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 19.0 | 61 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 21.0 | 72 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 22.0 | 64 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 18.0 | 63 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 21.5 | 62 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IFN-a2 | 52.0 | 71 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 48.5 | 70 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 44.5 | 64 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 44.0 | 59 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 36.0 | 71 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IFN-a2 | 52.0 | 60 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IFN-a2 | 72.0 | 62 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IFN-a2 | 58.0 | 72 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IFN-a2 | 66.5 | 64 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IFN-a2 | 62.0 | 63 |