Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Leptin | 1 | ng/mL | 3 | IL2-Ra | 16.0 | 57 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 13.0 | 57 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 13.5 | 62 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 13.0 | 55 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 14.0 | 65 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 11.0 | 74 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IL2-Ra | 13.0 | 51 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 12.5 | 50 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 13.0 | 72 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 14.0 | 48 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 14.0 | 67 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL2-Ra | 14.0 | 53 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 53.5 | 58 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 50.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 43.0 | 59 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 55.0 | 73 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 46.0 | 56 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 47.0 | 74 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 39.0 | 58 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 40.0 | 71 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 50.0 | 77 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 38.0 | 55 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 45.0 | 51 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL2-Ra | 39.0 | 73 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | IL2-Ra | 13.0 | 59 |