Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 3
IL-17
 44.0 75
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 3
IL-17
 48.5 84
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
IL-17
 50.5 70
RA2159 Adiponectin 5
ng/mL
 3
IL-17
 45.0 72
RA2159 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
IL-17
 46.5 84
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 45.0 78
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 53.0 62
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 44.0 64
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
IL-17
 49.0 69
N2586 Adiponectin 5
ng/mL
 3
IL-17
 48.0 73
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
IL-17
 48.0 55
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 46.0 66
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 50.5 62
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-17
 47.0 59
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
IL-17
 47.0 63
RA2159 IGF-I 100
ug/mL
 3
IL-17
 48.0 72
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
IL-17
 47.0 67
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-17
 44.0 72
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-17
 45.0 69
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-17
 45.0 77
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
IL-17
 48.5 68
RA2159 3
IL-17
 50.0 62
N2586 IGF-I 100
ug/mL
 3
IL-17
 49.0 63
N2586 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
IL-17
 42.5 52
N2586 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-17
 42.0 74