Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 2
IL-17
 70.0 55
N2586 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL-17
 65.0 57
N2586 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL-17
 71.0 57
N2586 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL-17
 63.0 61
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-17
 67.0 55
N2586 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
IL-17
 77.0 49
N2586 PD184352 0.1
uM
 2
IL-17
 51.0 51
RA2159 IL-1 alpha 100
ng/mL
 2
IL-17
 75.5 66
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 66.0 70
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 64.0 79
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 67.0 53
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 71.0 68
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 64.5 54
RA2159 Lestaurtinib 0.3
uM
 2
IL-17
 47.0 41
N2586 IL-1 alpha 100
ng/mL
 2
IL-17
 72.0 57
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 65.0 71
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 71.5 54
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 68.0 58
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 70.0 41
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-17
 67.5 48
N2586 Lestaurtinib 0.3
uM
 2
IL-17
 52.0 40
RA2159 IL-6 100
ug/mL
 2
IL-17
 62.0 52
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL-17
 53.0 61
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL-17
 57.5 62
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL-17
 51.5 64