Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Leptin 1
ng/mL
 1
IL-17
 54.0 76
RA2159 PD184352 0.1
uM
 Leptin 1
ng/mL
 1
IL-17
 46.0 57
RA2159 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 50.0 79
RA2159 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 50.0 54
RA2159 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 43.5 60
RA2159 IKK16 2.0
uM
 Leptin 1
ng/mL
 1
IL-17
 50.0 62
N2586 Leptin 1
ng/mL
 1
IL-17
 47.0 64
N2586 PD184352 0.1
uM
 Leptin 1
ng/mL
 1
IL-17
 44.0 58
N2586 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 46.5 60
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 39.5 80
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 1
IL-17
 45.0 54
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 1
IL-17
 43.5 48
RA2159 1
IL-17
 49.0 53
RA2159 PD184352 0.1
uM
 1
IL-17
 44.0 59
RA2159 Lestaurtinib 0.3
uM
 1
IL-17
 51.0 66
RA2159 Ruxolitinib 0.3
uM
 1
IL-17
 54.0 55
RA2159 Tofacitinib 0.3
uM
 1
IL-17
 44.0 61
RA2159 IKK16 2.0
uM
 1
IL-17
 50.0 50
RA2159 1
IL-17
 43.5 76
N2586 1
IL-17
 49.5 86
N2586 PD184352 0.1
uM
 1
IL-17
 53.0 75
N2586 Lestaurtinib 0.3
uM
 1
IL-17
 42.0 68
N2586 Ruxolitinib 0.3
uM
 1
IL-17
 46.0 63
N2586 Tofacitinib 0.3
uM
 1
IL-17
 52.0 67
N2586 IKK16 2.0
uM
 1
IL-17
 46.0 56