Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 78.5 | 40 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 77.5 | 56 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 79.0 | 76 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 79.0 | 77 | |
| RA2159 | 1 | IL-15 | 73.0 | 56 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 1 | IL-15 | 76.0 | 56 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 70.0 | 49 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 73.0 | 73 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 70.0 | 45 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 78.0 | 53 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-15 | 71.0 | 79 | |
| N2586 | 1 | IL-15 | 91.0 | 61 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-15 | 70.0 | 53 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 87.0 | 51 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 81.0 | 57 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 84.5 | 48 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 80.0 | 73 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 69.5 | 60 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | IL-15 | 71.5 | 74 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 78.5 | 52 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 94.0 | 55 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 78.0 | 40 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 69.5 | 58 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-15 | 87.0 | 43 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | IL-15 | 79.0 | 60 |