Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 62.0 | 55 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 52.5 | 60 | |
| RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 67.0 | 53 | |
| N2586 | IL-17A | 100 | ng/mL | 3 | IL-10 | 79.0 | 69 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 73.0 | 71 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 25.0 | 75 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 65.0 | 63 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 80.5 | 54 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 3 | IL-10 | 78.0 | 47 | |
| RA2159 | IL-6 | 100 | ug/mL | 3 | IL-10 | 52.5 | 40 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 81.0 | 57 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 62.0 | 59 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 73.0 | 61 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 57.0 | 53 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 64.0 | 59 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 3 | IL-10 | 60.5 | 58 | ||||
| N2586 | IL-6 | 100 | ug/mL | 3 | IL-10 | 75.5 | 74 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 72.5 | 54 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 69.0 | 60 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 103.0 | 69 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 92.0 | 58 | |
| N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-10 | 60.0 | 71 | |
| N2586 | Sigma A6730 | 3.0 | uM | 3 | IL-10 | 71.0 | 54 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 3 | IL-10 | 89.0 | 59 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-10 | 75.5 | 62 |