Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-17A 100
ng/mL
 2
IL-10
 57.5 62
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 49.5 60
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-10
 48.5 60
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 47.0 50
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 45.0 61
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-10
 50.0 39
RA2159 Tofacitinib 0.3
uM
 2
IL-10
 39.0 43
N2586 IL-17A 100
ng/mL
 2
IL-10
 86.0 57
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 78.0 52
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL-10
 64.0 50
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 57.5 64
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IL-10
 59.0 61
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IL-10
 62.0 59
N2586 Tofacitinib 0.3
uM
 2
IL-10
 60.5 42
RA2159 2
IL-10
 47.0 62
RA2159 EO1428 1.0
uM
 2
IL-10
 47.0 49
RA2159 PI103 0.1
uM
 2
IL-10
 53.0 53
RA2159 Sigma A6730 3.0
uM
 2
IL-10
 35.0 43
RA2159 JNK-IN-8 3.0
uM
 2
IL-10
 38.0 52
RA2159 JNK-IN-11 0.3
uM
 2
IL-10
 45.5 56
RA2159 IKK16 2.0
uM
 2
IL-10
 37.0 52
N2586 2
IL-10
 69.0 50
N2586 EO1428 1.0
uM
 2
IL-10
 51.5 42
N2586 PI103 0.1
uM
 2
IL-10
 52.0 43
N2586 Sigma A6730 3.0
uM
 2
IL-10
 59.5 56