Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-10 | 60.0 | 57 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-10 | 72.5 | 50 | |
| N2586 | 1 | IL-10 | 75.0 | 55 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-10 | 53.5 | 50 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 41.0 | 60 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 46.5 | 62 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 52.0 | 43 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 52.0 | 57 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 35.5 | 56 | |
| N2586 | Adiponectin | 5 | ng/mL | 1 | IL-10 | 56.0 | 60 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 62.0 | 35 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 71.0 | 49 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 51.0 | 57 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 42.0 | 54 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-10 | 72.0 | 47 | |
| RA2159 | Leptin | 1 | ng/mL | 1 | IL-10 | 42.0 | 58 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 57.0 | 50 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 48.0 | 59 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 69.0 | 53 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 60.5 | 60 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 47.5 | 46 | |
| N2586 | Leptin | 1 | ng/mL | 1 | IL-10 | 60.0 | 43 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 68.0 | 53 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 61.5 | 72 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 1 | IL-10 | 43.0 | 33 |