Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 616.0 | 79 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 886.5 | 92 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 305.0 | 75 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IL-8 | 1109.0 | 79 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 853.5 | 82 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 1005.0 | 69 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 1179.5 | 84 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 904.0 | 87 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IL-8 | 758.0 | 79 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IL-8 | 520.0 | 79 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 375.0 | 87 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 457.0 | 73 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 833.0 | 87 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 686.0 | 88 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 421.0 | 83 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IL-8 | 1820.0 | 82 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 1096.0 | 68 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 1276.0 | 79 | |
| N2586 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 1363.5 | 64 | |
| N2586 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 852.0 | 85 | |
| N2586 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IL-8 | 689.0 | 73 | |
| RA2159 | IGF-I | 100 | ug/mL | 3 | IL-8 | 600.0 | 64 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 473.0 | 72 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 356.0 | 77 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 795.5 | 74 |