Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-8 | 1790.5 | 54 | |
| N2586 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-8 | 1933.0 | 44 | |
| N2586 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 1 | IL-8 | 1413.0 | 75 | |
| N2586 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 1 | IL-8 | 948.0 | 31 | |
| N2586 | JNK-IN-11 | 0.3 | uM | 1 | IL-8 | 941.5 | 90 | ||||
| RA2159 | IGF-I | 100 | ug/mL | 1 | IL-8 | 399.5 | 56 | ||||
| RA2159 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 225.5 | 68 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 412.0 | 58 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 616.0 | 79 | |
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 644.0 | 105 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 219.0 | 73 | |
| RA2159 | 1 | IL-8 | 861.0 | 70 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 1 | IL-8 | 736.0 | 73 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 816.0 | 64 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 580.5 | 84 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 1102.5 | 60 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 809.0 | 41 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 1 | IL-8 | 389.0 | 88 | |
| N2586 | 1 | IL-8 | 1052.0 | 77 | |||||||
| RA2159 | Adiponectin | 5 | ng/mL | 1 | IL-8 | 462.5 | 80 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 1 | IL-8 | 174.0 | 85 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-8 | 233.0 | 83 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-8 | 695.0 | 58 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 1 | IL-8 | 720.0 | 73 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 1 | IL-8 | 233.5 | 94 |